coding – Communicable Diseases Research

Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS-CoV-2 from 946 whole-exome sequencing data in the Turkish population

Article

Published on 2022-11-012022-11-16
Journal: Journal of medical virology
[Category] COVID19(2023년), SARS, 변종, 치료기술,

Caring for people experiencing homelessness in times of crisis: Realities of essential service providers during the COVID-19 pandemic in Copenhagen, Denmark

Research article

Published on 2022-09-012022-10-05
Journal: International Journal of Disaster Risk Reduction
[Category] 변종,

Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival

Article

Published on 2022-08-272022-11-16
Journal: Viruses
[Category] SARS, 변종,

Developing a Long COVID Phenotype for Postacute COVID-19 in a National Primary Care Sentinel Cohort: Observational Retrospective Database Analysis

Observational Study

Published on 2022-08-112022-10-04
Journal: JMIR Public Health and Surveillance
[Category] 임상,

[키워드] 95% CI acute COVID-19 acute infection addition biomedical ontologies BioPortal Clinical characteristics clinical symptom clinically coded coding college Comorbidities complex computerized contribute COVID COVID-19 data accuracy data extracts data sets database develop Developing diagnosed Diagnosis Digital tool disease disease management Electronic health record English Epidemiology Ethnicity general practitioner General practitioners groups had no Health Hospital admission Hospitalization Hospitalized include individual Infection Laboratory Logistic regression Long Long COVID long-COVID management medical record systems nomenclature office ontological Ontology Oxford Patient phenotype postacute COVID-19 syndrome primary care problems public health RCGP recorded recruited Research retrospective RSC SARS-CoV-2 sentinel social class Sociodemographic Study protocol Surveillance surveillance. Symptom Systematized Nomenclature of Medicine used data Validity
[DOI] 10.2196/36989 PMC 바로가기 [Article Type] Observational Study

Coronavirus disease 2019 and the placenta: A literature review

코로나바이러스 질병 2019 및 태반: 문헌 검토

Review

Published on 2022-08-012022-09-11
Journal: Placenta
[Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Antigen Basigin canonical cathepsin B Cathepsin B/L caused CD147 CD26 Chain Reaction Clinical pathology coding coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CTL dipeptidyl peptidase Dipeptidyl peptidase-4 DPP4 electron microscopy eligible enzyme evaluate Express expressed Factor fetal furin IFITM1 immunohistochemistry implicated In situ hybridization interferon involved literature review Localization LY6E lymphocyte mechanism Microscopy multiple organ multiple organs nonspecific organ systems Particle Particles Pathogenesis pathogenesis of SARS-CoV-2 pathology permissiveness Placenta placental Placental infection placental pathology polymerase chain polymerase chain reaction Pregnancy pregnancy trimesters profile Proteases Protein Proteins receptor reduce RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptors Serine severe acute respiratory syndrome Coronavirus single-cell analysis single-cell analysis. the disease TMPRSS2 transmembrane transmembrane protein transmembrane serine protease Vascular viral pathogenesis Viral RNA virus
[DOI] 10.1016/j.placenta.2022.07.007 PMC 바로가기 [Article Type] Review

Spontaneous NLRP3 inflammasome-driven IL-1-β secretion is induced in severe COVID-19 patients and responds to anakinra treatment

Research article

Published on 2022-07-012022-10-05
Journal: The Journal of Allergy and Clinical Immunology
[Category] COVID19(2023년), SARS, 변종, 치료법,

[키워드] Activation acute respiratory syndrome Analysis analyzed Anti-inflammatory therapy apoptotic ASC Blood cDNA cell line circulating monocyte circulating monocytes coding confocal microscopy coronavirus COVID-19 Critically ill cytokine cytokine secretion Cytokine storm syndrome disease dissect driving effective Efficacy Evidence Frame IL-1 receptor antagonist IL-1β in vitro Infection Inflammasome inflammasomes Inflammation Inflammatory inflammatory parameters manifestation maturation mechanism NLRP3 NLRP3 inflammasome objective ORF3a pathway Patient patients with COVID-19 Phenotypes Plasma cytokine receptor protein reducing mortality regulated respond Result RNA sequencing SARS-CoV-2 SARS-CoV-2 protein secrete secretion severe coronavirus disease severe COVID-19 patient severe pneumonia shown Spontaneous transfection Treatment Trigger with COVID-19
[DOI] 10.1016/j.jaci.2022.05.029 [Article Type] Research article

The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune Genes

SARS-CoV-2에 감염된 세포의 번역 환경은 선천 면역 유전자의 억제를 나타냅니다

Article

Published on 2022-06-282022-09-11
Journal: mBio
[Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,

[키워드] abundantly expressed acute respiratory syndrome acute respiratory syndrome coronavirus Air-liquid interface airway Cell cell cultures cell line cells cellular cellular mRNAs chemokine ciliated ciliated cell coding coronavirus cytokine downregulation event help highlight host mRNA host response host responses immune immune response immune responses infected cells Inflammatory Innate innate immune innate immune response Interaction interferon-stimulated genes involved landscape mechanism mediators modulate mRNA mRNA translation mRNAs notable primary cells programmed frameshifting regulated respiratory ribo-seq ribosomal frameshifting ribosome ribosome profiling ribosomes RNAs SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication SARS-CoV-2-infected cell SARS-CoV-2-infected cells sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 suppression therapeutic therapeutic intervention These data transcriptional Transcriptional upregulation translated translation translation initiation translational translational repression unique upregulation Viral viral mRNA viral mRNAs virus virus replication virus-host interaction.
[DOI] 10.1128/mbio.00815-22 PMC 바로가기 [Article Type] Article

Risk Prediction for Acute Kidney Injury in Patients Hospitalized With COVID-19

Research article

Published on 2022-06-012022-10-05
Journal: Kidney Medicine
[Category] 바이오마커,

[키워드] 95% CI Acute kidney injury acute respiratory syndrome added age AKI baseline changes in coding Cohort cohort study cohorts comorbid condition conditions coronavirus coronavirus disease COVID-19 creatinine criteria D-dimer levels defined delta variant develop exposure ferritin Final High-sensitivity C-reactive protein hospital hospitalized patient Improving inflammatory biomarkers KDIGO Kidney injury laboratory data limitation longitudinal measure median Model model validation objective participant Patient patients patients hospitalized polymerase chain positive Potential predict prediction Predictive Predictive model rationale Result setting Vaccine validation cohort virus variants with COVID-19
[DOI] 10.1016/j.xkme.2022.100463 [Article Type] Research article

CAVES: A Novel Tool for Comparative Analysis of Variant Epitope Sequences

CAVES: 변이 에피토프 서열의 비교 분석을 위한 새로운 도구

Article

Published on 2022-05-262022-09-11
Journal: Viruses
[Category] COVID19(2023년), SARS, 변종,

Towards rainbow portable Cytophone with laser diodes for global disease diagnostics

Research

Published on 2022-05-232022-10-05
Journal: Scientific Reports
[Category] 바이오마커, 진단,